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Calponin-1 (R349O) Rabbit mAb

-AR0407

1
Cat No: AR0407
Size
Price
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Number
20ul
$120.00
In stock

0

40ul
$220.00
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0

100ul
$452.00
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0

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Main information

Target

Calponin-1

Reactivity

Human,Mouse,Rat

Applications

WB,IHC,IF,ELISA

MW (kDa)

33kD( Calculated)
33kD( Observed)

Host Species

Rabbit

Isotype

IgG,Kappa

Detailed information
Recommended Dilution Ratio
IHC 1:200-1:1000 WB 1:2000-1:10000 IF 1:200-1:1000 ELISA 1:5000-1:20000 Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#RH0011)
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C, Ship by ice bag)
MW(Calculated)
33kD
MW(Observed)
33kD
Clonality
Monoclonal
Clone
R349O
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Antigen & target information
Gene Name:
CNN1
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Protein Name:
Calponin-1
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Alias:
Calponin-1 ;
Basic calponin ;
Calponin H1, smooth muscle ;
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Database link
Organism Gene ID SwissProt
Human 1264; P51911;
Cell localization
Cytoplasm
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Function
Function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
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